CBD and hemp extracts are not dosed like microdosing or macrodosing. There is no universal amount that works for everyone, as individual factors such as body chemistry, product format, and cannabinoid bioavailability can influence how CBD is experienced.
For this reason, personal adjustment is often required. If you are unsure, or if you use prescription products, consult a qualified healthcare professional familiar with cannabinoids before use.
General CBD Dosing Guide
- Start low and adjust gradually
Many adults begin with small daily amounts, increasing slowly only if needed. - CBD is non-intoxicating
CBD does not produce psychoactive effects associated with THC. - No known dependency
CBD is not considered addictive and tolerance does not typically develop. - Consistency matters
Effects may not be immediate. Some users report noticing changes after several days of regular use. - Less may be sufficient
Broad-spectrum hemp extracts may be effective at lower amounts than isolated CBD. - Individual response varies
Body weight alone does not determine an effective amount. - Medication interactions
CBD dosing guide indicates that CBD may influence how certain substances are metabolised. If using other products, begin with very low amounts or choose formats that avoid first-pass liver metabolism (e.g. topical use). Seek professional advice when combining products.
What Does Research Indicate About CBD Safety & Use?
Scientific interest in cannabidiol (CBD) continues to grow, with studies exploring its safety profile and general tolerability.
CBD Safety & Side Effects
Some preclinical studies have raised questions about potential liver effects at very high doses. For example, a 2019 animal study observed liver stress at doses comparable to those used in prescription-grade CBD medicines. However, limited human data suggests that short-term use of high-dose CBD did not show liver-related effects in healthy adults.
Research on reproductive effects is currently based mainly on animal models. Human studies using single or short-term doses of CBD (300–600 mg) did not show changes in reproductive hormones, though long-term data remains limited.
Important: Clinical studies often use CBD isolate at pharmaceutical doses, which differ significantly from typical consumer products. Individual response may vary depending on dosage, formulation, and personal factors.
CBD Amounts Used According to Research
CBD Dosage for Pain
In observational studies involving several hundred participants, daily CBD amounts ranging from 40 mg to 300 mg were associated with reported improvements in comfort and quality of life. Results varied between individuals.
CBD Dosage for Stress or Anxiety
Most anxiety-related studies have examined CBD isolate at doses between 300–600 mg per day. Some findings suggest a dose-dependent response, where lower amounts may be perceived differently than higher ones.
CBD Dosage for Sleep
In one study, participants used 25 mg of CBD daily for one month, with a majority reporting improved sleep quality. Evening use was common in this research setting.
CBD Dosage Chart
| Body Weight | Low (Starting) Dose | Medium Dose | High Dose |
| 100 lbs | 10-20 mg | 21-49 mg | 50-60 mg |
| 110 lbs | 11-22 mg | 23-54 mg | 55-66 mg |
| 120 lbs | 12-24 mg | 25-59 mg | 60-72 mg |
| 130 lbs | 13-26 mg | 27-64 mg | 65-78 mg |
| 140 lbs | 14-28 mg | 29-69 mg | 70-84 mg |
| 150 lbs | 15-30 mg | 31-74 mg | 75-90 mg |
| 160 lbs | 16-32 mg | 33-79 mg | 80-96 mg |
| 170 lbs | 17-34 mg | 35-84 mg | 85-102 mg |
| 180 lbs | 18-36 mg | 37-89 mg | 90-108 mg |
| 190 lbs | 19-38 mg | 39-94 mg | 95-114 mg |
| 200 lbs | 20-40 mg | 41-99 mg | 100-120 mg |
| 210 lbs | 21-42 mg | 43-104 mg | 105-126 mg |
| 220 lbs | 22-44 mg | 45-109 mg | 110-132 mg |
| 230 lbs | 23-46 mg | 47-114 mg | 115-138 mg |
| 240 lbs | 24-48 mg | 49-119 mg | 120-144 mg |
| 250 lbs | 25-50 mg | 51-124 mg | 125-150 mg |
| 260 lbs | 26-52 mg | 53-129 mg | 130-156 mg |
| 270 lbs | 27-54 mg | 55-134 mg | 135-162 mg |
Important Consumer Information
- CBD is not a medicinal product
- Not intended to diagnose, treat, cure, or prevent disease
- Individual experiences may vary
- Consult a qualified healthcare professional if using medications
- Avoid use during pregnancy or breastfeeding